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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094438Generated: November 1, 2026

2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamine → HCID 58007559, compound

https://huagongshe.com/reaction/1094438

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamineHCID 18071344—
Reactant4-bromo-1-chloro-2-cyclopropoxybenzeneHCID 58007571—
ProductHCID 58007559HCID 58007559—

Reaction Steps

In analogy to the procedure described for the synthesis example 71 (step 1), the title compound (4-chloro-3-cyclopropoxy-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine (MS m/e: 357.1 [M+H]+) was prepared from (4-bromo-1-chloro-2-cyclopropoxy-benzene instead of 6-bromo-2,3-dihydro-benzofuran and 2-(5-trifluoromethyl-pyridin-2-yl)-ethylamine instead of 2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133909B2
Source datasetuspto-grants-2012_03
ORD IDord-2e5160ff40b14206b0de85f1d0a9df00
Source noteuspto-grants-2012_03