2,6-Lutidine → HCID 57582360, compound

HRID 1094787Notes

Reaction equation

HRID 1094787 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[C:9]1[C:10]([NH2:16])=[N:11][C:12]([NH2:15])=[CH:13][CH:14]=1.N1C(C)=CC=CC=1C.[O:25]1[N:29]=[CH:28][C:27]([C:30](O)=[O:31])=[N:26]1>>[NH2:16][C:10]1[N:11]=[C:12]([NH:15][C:30]([C:27]2[CH:28]=[N:29][O:25][N:26]=2)=[O:31])[CH:13]=[CH:14][C:9]=1[C:3]1[CH:4]=[C:5]([Cl:8])[CH:6]=[CH:7][C:2]=1[Cl:1]

Participants

4

Reactant 3

HCID 79372,6-LutidineHCID 14155241,2,5-oxadiazole-3-carboxylic acidHCID 66637020HCID 66637020, compound

Product 1

HCID 57582360HCID 57582360, compound

Procedure

N-[6-Amino-5-(2,5-dichlorophenyl)pyridin-2-yl]-1,2,5-oxadiazole-3-carboxamide was prepared by a method analogous to Method A, as described for Example 1 above, using 3-(2,5-dichlorophenyl)pyridine-2,6-diamine (Preparation 7), 1 equivalent lutidine and 1 equivalent acid chloride prepared from 1,2,5-oxadiazole-3-carboxylic acid.

Sources & evidence

ORD record
ord-a59effab2fd64938b6e740ce64ada8f9
Source dataset
uspto-grants-2012_03
Patent number
US08134007B2

Reaction notes

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