Acetonitrile → HCID 57582356, compound

HRID 1094817Notes

Reaction equation

HRID 1094817 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[OH:9].BrC[CH2:12][CH2:13][O:14][CH3:15].[C:16](#N)C>>[Br:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[O:9][CH2:12][CH:13]([O:14][CH3:15])[CH3:16]

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 5245511-Bromo-3-methoxypropaneHCID 6054722-Bromo-4-fluorophenol

Product 1

HCID 57582356HCID 57582356, compoundYield 88%

Procedure

2-Bromo-4-fluorophenol (950 mg, 4.97 mmol) and 1-bromo-3-methoxypropane (1000 mg, 6.53 mmol) in acetonitrile (10 ml) was treated as for preparation 62 to afford crude title compound as a yellow oil (1.16 g, 88%).

Sources & evidence

ORD record
ord-242bc349ebce49e0bde6b0a4f70f5558
Source dataset
uspto-grants-2012_03
Patent number
US08134007B2

Reaction notes

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