HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86630488, compound → HCID 76597821, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86630488 | HCID 86630488 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 76597821 | HCID 76597821 | 56% |
Reaction Steps
t-Butyl 3-(5-{1-[4-Hydroxy-5-(4-trifluoromethylphenyl)thiophen-3-yl]ethylidenehydrazinocarbonyl}-N-methylthiophene-2-carboxamido)propionate (30 mg, 0.05 mmol) was stirred with trifluoroacetic acid (300 μL) at room temperature for 15 minutes. The reaction solution was concentrated, and after addition of ether the resulting solid was collected by filtration to give the desired product (yield 56%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134013B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-068bef0487fd49e29c7770d5d19970c5 |
| Source note | uspto-grants-2012_03 |