HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dimethylphenol → 5-Bromo-2-(2,5-dimethyl-phenoxy)-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dimethylphenol | HCID 7267 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Bromo-2-fluorobenzaldehyde | HCID 736327 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | 5-Bromo-2-(2,5-dimethyl-phenoxy)-benzaldehyde | HCID 57743410 | 98.3% |
Reaction Steps
In a manner similar to the method described in Example 50a, 5-bromo-2-fluorobenzaldehyde (2.1 g, 10 mmol) (Alfa) was reacted with 2,5-dimethylphenol (1.4 g, 11 mmol) and K2CO3 in N,N-dimethylacetamide to give 5-bromo-2-(2,5-dimethyl-phenoxy)-benzaldehyde as an orange oil (Yield 3 g, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-ff1a64f8599c412bb3e0af7a59fd3965 |
| Source note | uspto-grants-2012_03 |