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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1095099Generated: November 1, 2026

Potassium Carbonate → HCID 57743275, compound

https://huagongshe.com/reaction/1095099

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantMethyl VanillateHCID 19844—
Reactant5-Bromo-2-fluorobenzaldehydeHCID 736327—
SolventDimethylacetamideHCID 31374—
ProductHCID 57743275HCID 5774327592%

Reaction Steps

In a manner similar to the method described in Example 50a, 5-bromo-2-fluorobenzaldehyde (4.1 g, 20 mmol) (Alfa) was reacted with methyl vanillate (3.64 g, 20 mmol)(Aldrich) and K2CO3 in N,N-dimethylacetamide to give 4-(4-bromo-2-formyl-phenoxy)-3-methoxy-benzoic acid methyl ester as a white solid (Yield 3.1 g, 92%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08134001B2
Source datasetuspto-grants-2012_03
ORD IDord-d4bf962d08144622b8ca4e46d1722d29
Source noteuspto-grants-2012_03