反应详情

In a manner similar to the method described in Example 60b, 2-[4-(2-hydroxy-ethoxy)-phenoxy]-5-iodo-benzaldehyde (3.8 g, 9.8 mmol) was reacted with tert-butyldimethylchlorosilane (1.8 g, 12 mmol) and imidazole in N,N-dimethylformamide to give 2-{4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-phenoxy}-5-iodo-benzaldehyde as a white solid (Yield 4.7 g, 95%).