反应详情

In a manner similar to the method described in Example 60b, 5-chloro-2-[4-(2-hydroxy-ethoxy)-phenoxy]-benzaldehyde (1.68 g, 5.7 mmol) was reacted with tert-butyldimethylchlorosilane (1.3 g, 8.6 mmol) and imidazole in N,N-dimethylformamide to give 2-{4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-phenoxy}-5-chloro-benzaldehyde as a white solid (Yield 2.1 g, 90%).