HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-Bromo-2-(2,6-dimethyl-pyridin-4-yloxy)-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Bromo-2-fluorobenzaldehyde | HCID 736327 | — |
| Reactant | HCID 178429033 | HCID 178429033 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | 5-Bromo-2-(2,6-dimethyl-pyridin-4-yloxy)-benzaldehyde | HCID 57743267 | — |
Reaction Steps
In a manner similar to the method described in Example 50a, 5-bromo-2-fluorobenzaldehyde (4.1 g, 20 mmol) (Alfa) was reacted with 2,6-dimethyl-4-hydroxypyridine (2.5 g, 20 mmol) and K2CO3 in N,N-dimethylacetamide to give 5-bromo-2-(2,6-dimethyl-pyridin-4-yloxy)-benzaldehyde as an off white solid (Yield 6 g, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-006585e246ea46e5b9ff17fa0656cf8b |
| Source note | uspto-grants-2012_03 |