HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 57743200, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-(4-Hydroxyphenyl)propanol | HCID 82452 | — |
| Reactant | 5-Bromo-2-fluorobenzaldehyde | HCID 736327 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57743200 | HCID 57743200 | 99.4% |
Reaction Steps
In a manner similar to the method described in Example 50a, 5-bromo-2-fluorobenzaldehyde (5.5 g, 27 mmol) (Alfa) was reacted with 3-(4-hydroxyphenyl)-1-propanol (4.5 g, 30 mmol)(Aldrich) and K2CO3 in N,N-dimethylacetamide to give 5-bromo-2-[4-(3-hydroxy-propyl)-phenoxy]-benzaldehyde as a brown oil (Yield 9 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-ec54b7395a55432085a641e23ee3a2be |
| Source note | uspto-grants-2012_03 |