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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1095131Generated: November 1, 2026

Potassium Carbonate → HCID 57743200, compound

https://huagongshe.com/reaction/1095131

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant3-(4-Hydroxyphenyl)propanolHCID 82452—
Reactant5-Bromo-2-fluorobenzaldehydeHCID 736327—
SolventDimethylacetamideHCID 31374—
ProductHCID 57743200HCID 5774320099.4%

Reaction Steps

In a manner similar to the method described in Example 50a, 5-bromo-2-fluorobenzaldehyde (5.5 g, 27 mmol) (Alfa) was reacted with 3-(4-hydroxyphenyl)-1-propanol (4.5 g, 30 mmol)(Aldrich) and K2CO3 in N,N-dimethylacetamide to give 5-bromo-2-[4-(3-hydroxy-propyl)-phenoxy]-benzaldehyde as a brown oil (Yield 9 g, 99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08134001B2
Source datasetuspto-grants-2012_03
ORD IDord-ec54b7395a55432085a641e23ee3a2be
Source noteuspto-grants-2012_03