HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 57743367, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | trimethyl-1H-pyrazol-4-ol | HCID 12498505 | — |
| Reactant | 2-Fluoro-5-iodobenzaldehyde | HCID 16217058 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57743367 | HCID 57743367 | 97.2% |
Reaction Steps
In a manner similar to the method described in Example 50a, 2-fluoro-5-iodobenzaldehyde (5.84 g, 23.4 mmol) (Aldrich) was reacted with 1,3,5-trimethyl-1H-pyrazol-4-ol (3.24 g, 25.7 mmol) and K2CO3 in N,N-dimethylacetamide to give 5-iodo-2-(1,3,5-trimethyl-1H-pyrazol-4-yloxy)-benzaldehyde as a yellow solid (Yield 8.1 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-88d8958e6b2b4b7bb37f4e21792483f7 |
| Source note | uspto-grants-2012_03 |