HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 57743358, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Bromo-2-fluorobenzaldehyde | HCID 736327 | — |
| Reactant | trimethyl-1H-pyrazol-4-ol | HCID 12498505 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57743358 | HCID 57743358 | 100.3% |
Reaction Steps
In a manner similar to the method described in Example 50a, 5-bromo-2-fluoro-benzaldehyde (2 g, 10 mmol) (Acros) was reacted with 1,3,5-trimethyl-1H-pyrazol-4-ol (1.3 g, 10 mmol) and K2CO3 in N,N-dimethylacetamide to give 5-bromo-2-(1,3,5-trimethyl-1H-pyrazol-4-yloxy)-benzaldehyde as a white solid (Yield 3.1 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-cb48b1e68cf642b8ac3ef765a37d7555 |
| Source note | uspto-grants-2012_03 |