HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1095181Generated: November 1, 2026
3-Fluorobenzaldehyde → HCID 5027553, compound
https://huagongshe.com/reaction/1095181
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Fluorobenzaldehyde | HCID 68009 | — |
| Reactant | 6-Chloro-1,3-dihydroindol-2-one | HCID 736344 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Piperidine | HCID 8082 | — |
| Product | HCID 5027553 | HCID 5027553 | — |
Reaction Steps
6-Chloro-1,3-dihydro-indol-2-one (Aldrich, 7.5 g, 44.92 mmol) was treated with 3-fluoro-benzaldehyde (Aldrich, 5.57 g, 44.92 mmol) in methanol (50 mL) and piperdine (0.2 mL). The mixture was heated at 75° C. overnight and then cooled to room temperature. The solid was filtered and dried to give a yellow solid. 8.8 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08134001B2 |
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| Source dataset | uspto-grants-2012_03 |
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| ORD ID | ord-0c2c99ac9d5c47e7ac99552acc496e02 |
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| Source note | uspto-grants-2012_03 |
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