Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Cyanophenol | HCID 13019 | — |
| Reactant | 2,3-Difluorobenzaldehyde | HCID 137664 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 43313256 | HCID 43313256 | — |
Reaction Steps
To stirred solution of 4-cyanophenol (Aldrich, 5.00 g, 42 mmol) in DMF (100 mL), potassium carbonate (63 mmol) and 2-4, difluoro-benzaldehyde (Aldrich, 5.97 g, 42 mmol) were added and the mixture was stirred at 90° C. overnight. The mixture was cooled to room temperature and poured into water. The solid was filtered and dried to give a pale yellow solid. 5.2 g MS (H+), 242.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08134001B2 |
|---|
| Source dataset | uspto-grants-2012_03 |
|---|
| ORD ID | ord-da5e245c07f349c68718c3b01fd4fc1a |
|---|
| Source note | uspto-grants-2012_03 |
|---|
