Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1095199Generated: October 31, 2026

6-Chloro-1,3-dihydroindol-2-one → HCID 66641200, compound

https://huagongshe.com/reaction/1095199

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-1,3-dihydroindol-2-oneHCID 736344—
Reactant5-Chloro-2-fluorobenzaldehydeHCID 2773586—
ProductHCID 66641200HCID 66641200—

Reaction Steps

In a manner similar to the methods described in Examples 1a and 1b, 6-chloro-1,3-dihydro-indol-2-one (Aldrich) reacted with 5-chloro-2-fluoro-benzaldehyde to give 6-chloro-3-[1-(5-chloro-2-fluoro-phenyl)-methylidene]-2-oxo-2,3-dihydro-indole, which was subsequently protected with (t-BuOCO)2O and DMAP.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08134001B2
Source datasetuspto-grants-2012_03
ORD IDord-8b0f707924ca428da06d2b3d350b67e0
Source noteuspto-grants-2012_03