HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 86631798, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Cyclohexyl methanesulfonate | HCID 85308 | — |
| Reactant | 5-Iodosalicylaldehyde | HCID 252612 | — |
| Product | HCID 86631798 | HCID 86631798 | — |
Reaction Steps
In a manner similar to the methods described in Example 128a and 112b, 5-iodo-2-hydroxy-benzaldehyde was reacted with methanesulfonic acid cyclohexyl ester and potassium carbonate to give 5-Iodo-2-(cyclohexyloxy)-benzaldehyde, which was subsequently reacted with LHMDS, acetyl chloride, triethylamine and chloro-trimethyl-silane to give the title compound and directly used for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-93223e36d0394a768aaaef1baa44de7d |
| Source note | uspto-grants-2012_03 |