HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → 4'-(Carbethoxymethylamino)-5,6,7-trimethoxyflavone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4'-Amino-5,6,7-trimethoxyflavone | HCID 10019325 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4'-(Carbethoxymethylamino)-5,6,7-trimethoxyflavone | HCID 66783370 | — |
Reaction Steps
Similar to the preparation of 12a, the title compound is prepared from the reaction of 4′-amino-5,6,7-trimethoxyflavone, 10a, (654 mg, 2 mmol), ethyl bromoacetate (367 mg, 2.2 mmol), and anhydrous potassium carbonate (0.5 g) in methanol (40 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138165B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-cb4e5a5eb9a84919baf20a60fa8bf43d |
| Source note | uspto-grants-2012_03 |