反应详情

The product from step (viii) (13 g) was dissolved in methanol (100 ml) and 4N—HCl in dioxane (10 ml) added. The reaction mixture was stirred at rt for 24 h. The resultant was concentrated under reduced pressure and aqueous NaHCO3 added to pH 8. The suspension was filtered and the solid collected and dried under reduced pressure to give the subtitle compound. Yield 11 g.

1. concentrationThe resultant was concentrated under reduced pressure and aqueous NaHCO3
2. additionadded to pH 8
3. filtrationThe suspension was filtered
4. customthe solid collected
5. customdried under reduced pressure