Hydrochloric Acid → HCID 24962426, compound

HRID 1095336Notes

Reaction equation

HRID 1095336 reaction equation
[NH2:1][C:2]1[N:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])[N:8]=[C:7]2[C:3]=1[NH:4][C:5](=[O:42])[N:6]2[CH2:16][CH2:17][CH2:18][N:19]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[C:33]([CH2:37][C:38]([O:40][CH3:41])=[O:39])[CH:32]=1)[C:20](=[O:29])[CH2:21][C:22]([O:24][C:25](C)(C)C)=[O:23].Cl>CO.O1CCOCC1>[NH2:1][C:2]1[N:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])[N:8]=[C:7]2[C:3]=1[NH:4][C:5](=[O:42])[N:6]2[CH2:16][CH2:17][CH2:18][N:19]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[C:33]([CH2:37][C:38]([O:40][CH3:41])=[O:39])[CH:32]=1)[C:20](=[O:29])[CH2:21][C:22]([O:24][CH3:25])=[O:23]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 86645626HCID 86645626, compound

Product 1

HCID 24962426HCID 24962426, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 312751,4-DioxaneSolvent

Procedure

The product from step (i) (100 mg) was dissolved in methanol (3 ml) and 4N—HCl in dioxane added. The mixture was stirred at rt for 5 h and purified by RPHPLC, which afforded the title compound. Yield 80 mg

Workup

  1. custompurified by RPHPLC, which

Sources & evidence

ORD record
ord-07c4f486a942446ab43263629178e7fc
Source dataset
uspto-grants-2012_03
Patent number
US08138172B2

Reaction notes

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