反应详情

Tryptamine (3.04 g, 19.0 mmol) and phthalic anhydride (3.00 g, 20.0 mmol) were boiled for 12 h in a water separator. The solvent was distilled off i. vac. and the residue was dissolved in methylene chloride. Product was precipitated out by addition of cyclohexane and the precipitate was filtered off with suction and dried. Yield: 4.46 g (Ind-1; 87%)

1. distillationThe solvent was distilled off i
2. dissolutionand the residue was dissolved in methylene chloride
3. customProduct was precipitated out by addition of cyclohexane
4. filtrationthe precipitate was filtered off with suction
5. customdried