HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethyl-9-(4-hydroxyphenyl)-1-oxa-4,9-diazaspiro[5,5]undecan-3-one → 1-(3-Bromopropyl)piperidine Hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethyl-9-(4-hydroxyphenyl)-1-oxa-4,9-diazaspiro[5,5]undecan-3-one | HCID 66783271 | — |
| Reactant | (3S)-1-(3-bromopropyl)-3-methylpiperidine hydrobromide | HCID 66784168 | — |
| Product | 1-(3-Bromopropyl)piperidine Hydrobromide | HCID 20135772 | — |
Reaction Steps
The entitled compound was obtained as a pale yellow solid, according to the same method as in Example 5-(c) or according to a method similar to it but using 4-ethyl-9-(4-hydroxyphenyl)-1-oxa-4,9-diazaspiro[5,5]undecan-3-one obtained in Example 5-3-(b), and (3S)-1-(3-bromopropyl)-3-methylpiperidine hydrobromide obtained in Reference Example 4 in place of 1-(3-bromopropyl)piperidine hydrobromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138206B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-271f5b1d857040b19f3a0e667364b4cc |
| Source note | uspto-grants-2012_03 |