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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1095826Generated: October 27, 2026

4-Ethyl-9-(4-hydroxyphenyl)-1-oxa-4,9-diazaspiro[5,5]undecan-3-one → 1-(3-Bromopropyl)piperidine Hydrobromide

https://huagongshe.com/reaction/1095826

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Ethyl-9-(4-hydroxyphenyl)-1-oxa-4,9-diazaspiro[5,5]undecan-3-oneHCID 66783271—
Reactant(3S)-1-(3-bromopropyl)-3-methylpiperidine hydrobromideHCID 66784168—
Product1-(3-Bromopropyl)piperidine HydrobromideHCID 20135772—

Reaction Steps

The entitled compound was obtained as a pale yellow solid, according to the same method as in Example 5-(c) or according to a method similar to it but using 4-ethyl-9-(4-hydroxyphenyl)-1-oxa-4,9-diazaspiro[5,5]undecan-3-one obtained in Example 5-3-(b), and (3S)-1-(3-bromopropyl)-3-methylpiperidine hydrobromide obtained in Reference Example 4 in place of 1-(3-bromopropyl)piperidine hydrobromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08138206B2
Source datasetuspto-grants-2012_03
ORD IDord-271f5b1d857040b19f3a0e667364b4cc
Source noteuspto-grants-2012_03