Acetone → HCID 66783283, compound

HRID 1095828Notes

Reaction equation

HRID 1095828 reaction equation
[CH:1]1([N:5]2[CH2:10][C:9]3([CH2:15][CH2:14][N:13]([C:16]4[CH:21]=[CH:20][C:19]([O:22][CH:23]5[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]5)=[CH:18][CH:17]=4)[CH2:12][CH2:11]3)[O:8][CH2:7][C:6]2=[O:29])[CH2:4][CH2:3][CH2:2]1.[CH3:30][C:31]([CH3:33])=O>>[CH:1]1([N:5]2[CH2:10][C:9]3([CH2:15][CH2:14][N:13]([C:16]4[CH:17]=[CH:18][C:19]([O:22][CH:23]5[CH2:28][CH2:27][N:26]([CH:31]([CH3:33])[CH3:30])[CH2:25][CH2:24]5)=[CH:20][CH:21]=4)[CH2:12][CH2:11]3)[O:8][CH2:7][C:6]2=[O:29])[CH2:2][CH2:3][CH2:4]1

Participants

3

Reactant 2

HCID 180AcetoneHCID 66783676HCID 66783676, compound

Product 1

HCID 66783283HCID 66783283, compound

Procedure

The entitled compound was obtained as an orange oily substance, according to the same method as in Example 4-15-(a) or according to a method similar to it but using 4-cyclobutyl-9-[4-(piperidin-4-yloxy)phenyl]-1-oxa-4,9-diazaspiro[5,5]undecan-3-one obtained in Example 8-5-(a) and acetone.

Workup

  1. customThe entitled compound was obtained as an orange oily substance

Sources & evidence

ORD record
ord-7e1f4cf2fe334ff98dc2bece72605287
Source dataset
uspto-grants-2012_03
Patent number
US08138206B2

Reaction notes

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