HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromomethyl-nicotinic acid methyl ester → HCID 59508739, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromomethyl-nicotinic acid methyl ester | HCID 12752237 | — |
| Reactant | 3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenol | HCID 57421264 | — |
| Product | HCID 59508739 | HCID 59508739 | — |
Reaction Steps
The title compound was prepared in analogy to Example 93, step 7 from 3-chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenol (obtained in Example 19, step 5) by alkylation with methyl-6-(bromomethyl)-nicotinate [CAS Reg. No. 131803-48-0]. MS (m/e)=515.0 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138189B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-9902d198a6664311a7bc92d7459c7548 |
| Source note | uspto-grants-2012_03 |