HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4S)-6-Azaspiro[2.5]octan-4-ol hydrochloride → HCID 59159315, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4S)-6-Azaspiro[2.5]octan-4-ol hydrochloride | HCID 44541812 | — |
| Reactant | HCID 86638384 | HCID 86638384 | — |
| Product | HCID 59159315 | HCID 59159315 | 60% |
Reaction Steps
In analogy to the procedure described in example 1K, (S)-4-oxo-2-[7-oxo-4-(3-trifluoromethoxy-phenyl)-[1,4]diazepan-1-yl]-butyric acid methyl ester and (S)-6-aza-spiro[2.5]octan-4-ol hydrochloride (intermediate 2) gave the title compound in 60% yield as light yellow viscous oil. MS: 500.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138175B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-670287af028d4d718fbe34281c87dad6 |
| Source note | uspto-grants-2012_03 |