HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66783501, compound → HCID 59159249, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66783501 | HCID 66783501 | — |
| Reactant | HCID 86638387 | HCID 86638387 | — |
| Product | HCID 59159249 | HCID 59159249 | 63% |
Reaction Steps
In analogy to the procedure described in example 1K, (S)-4-methoxy-3-[7-oxo-4-(3-trifluoromethyl-phenyl)-[1,4]diazepan-1-yl]-butyraldehyde (example 23D) and (3S,5S)-5-methyl-piperidin-3-ol hydrochloride (intermediate 4) gave the title compound in 63% yield as light yellow gum. MS: 458.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138175B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-0c3f3a8266a344ed82465361eb667c30 |
| Source note | uspto-grants-2012_03 |