HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoropiperidine → 4-[3-(4-Fluoro-piperidin-1-yl)-propyl]-1-(3-trifluoromethyl-phenyl)-[1,4]diazepan-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoropiperidine | HCID 2759159 | — |
| Reactant | 3-[7-Oxo-4-(3-trifluoromethyl-phenyl)-[1,4]diazepan-1-yl]-propionaldehyde | HCID 86638388 | — |
| Product | 4-[3-(4-Fluoro-piperidin-1-yl)-propyl]-1-(3-trifluoromethyl-phenyl)-[1,4]diazepan-5-one | HCID 59159295 | — |
Reaction Steps
The title compound was prepared from 3-[7-oxo-4-(3-trifluoromethyl-phenyl)-[1,4]diazepan-1-yl]-propionaldehyde (Example 34C) and 4-fluoropiperidine in analogy to example 34D. MS: 402.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138175B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-ffba138fbbff4a5588cee504758a74e0 |
| Source note | uspto-grants-2012_03 |