HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Iodo-3-(trifluoromethoxy)benzene → 4-(3-Piperidin-1-yl-propyl)-1-(3-trifluoromethoxy-phenyl)-[1,4]diazepan-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Iodo-3-(trifluoromethoxy)benzene | HCID 2777293 | — |
| Reactant | 4-(3-Piperidin-1-yl-propyl)-[1,4]diazepan-5-one | HCID 66783026 | — |
| Product | 4-(3-Piperidin-1-yl-propyl)-1-(3-trifluoromethoxy-phenyl)-[1,4]diazepan-5-one | HCID 59159288 | — |
Reaction Steps
The title compound was prepared from 4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one (Example 33B) and 1-iodo-3-trifluoromethoxy-benzene in analogy to example 33. MS: 400.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138175B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-b79e35eedc2642f497451a397e547a2a |
| Source note | uspto-grants-2012_03 |