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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1096246Generated: November 3, 2026

HCID 66783287, compound → HCID 66783071, compound

https://huagongshe.com/reaction/1096246

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66783287HCID 66783287—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 66783071HCID 6678307183%

Reaction Steps

A solution of (R)-2-methyl-5-oxo-4-(3-piperidin-1-yl-propyl)-[1,4]diazepane-1-carboxylic acid benzyl ester 1.0 g (3 mmol) in MeOH (20 ml) was stirred with 10% palladium on charcoal under an atmosphere of hydrogen for 1 h. Filtration and concentrated afforded the title compound 0.6 g (83%) as a colorless oil. MS: 254.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08138175B2
Source datasetuspto-grants-2012_03
ORD IDord-f8f9772512124b1f9dfe774c6502e8da
Source noteuspto-grants-2012_03