HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66783287, compound → HCID 66783071, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66783287 | HCID 66783287 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66783071 | HCID 66783071 | 83% |
Reaction Steps
A solution of (R)-2-methyl-5-oxo-4-(3-piperidin-1-yl-propyl)-[1,4]diazepane-1-carboxylic acid benzyl ester 1.0 g (3 mmol) in MeOH (20 ml) was stirred with 10% palladium on charcoal under an atmosphere of hydrogen for 1 h. Filtration and concentrated afforded the title compound 0.6 g (83%) as a colorless oil. MS: 254.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138175B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-f8f9772512124b1f9dfe774c6502e8da |
| Source note | uspto-grants-2012_03 |