HCID 66783136, compound → HCID 63597022, compound

Participants

Reaction Steps

A solution of 3-methyl-4-(4-nitro-3-trifluoromethyl-phenyl)-piperazin-2-one (118 mg, 0.39 mmol) in MeOH (2 mL) was stirred at RT under a hydrogen atmosphere (1 bar) in the presence of palladium (10% on activated charcoal, 20 mg), then after 45 min insoluble material was removed by filtration through diatomaceous earth. The filtrate was evaporated to afford the title compound (98 mg, 92%). Light yellow viscous oil, MS: 274.1 (M+H)+.

Provenance & Evidence