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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1096834Generated: November 1, 2026

Cyclopropylamine → (3-Chloro-2-methylbenzyl)cyclopropylamine

https://huagongshe.com/reaction/1096834

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
Reactant3-Chloro-2-methylbenzoic acidHCID 82010—
Reactant3-chloro-N-cyclopropyl-2-methylbenzamideHCID 66784385—
Product(3-Chloro-2-methylbenzyl)cyclopropylamineHCID 66783779—

Reaction Steps

Prepared from 3-chloro-2-methylbenzoic acid (4.80 g, 28.1 mmol) and cyclopropylamine according to above-described procedures C and E (5.50 g, quantitative over 2 steps). LC-MS (3-chloro-N-cyclopropyl-2-methylbenzamide): tR=0.81 min, ES+: 210.11; LC-MS (title compound): tR=0.62 min, ES+: 196.05.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08138340B2
Source datasetuspto-grants-2012_03
ORD IDord-20610c6c30c94691b95a484c91290958
Source noteuspto-grants-2012_03