反应详情

温度

50 °C

Aqueous 2 N sodium hydroxide solution (8.4 mL) was added to an MeOH (85 mL) solution of methyl 2-phenyl-6-(tetrazol-5-yl)pyridine-4-carboxylate (3.19 g), and stirred at 50° C. for 4 hours. With cooling with ice, 2N hydrochloric acid (16.8 mL) and water were added to it, the formed precipitate was taken out through filtration, washed with water and dried to obtain the title compound as a flesh-colored powder.

1. additionwere added to it
2. filtrationthe formed precipitate was taken out through filtration
3. washwashed with water
4. customdried