反应详情

A trifluoroacetic acid (5 mL) solution of methyl 3-{[ethoxymethyl]tetrazol-5-yl}-5-pyrrolidin-1-ylbenzoate (127 mg) was stirred at room temperature for 2 hours and then at 80° C. for 2 hours. The reaction liquid was concentrated under reduced pressure, the residue was purified through reversed-phase high-performance liquid chromatography [acetonitrile/water+0.1% trifluoroacetic acid] to obtain the title compound as a yellow powder.

1. customThe reaction liquid
2. concentrationwas concentrated under reduced pressure
3. customthe residue was purified through reversed-phase high-performance liquid chromatography [acetonitrile/water+0.1% trifluoroacetic acid]