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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1096969Generated: October 30, 2026

Hydrochloric Acid → HCID 178524188, compound

https://huagongshe.com/reaction/1096969

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethanolHCID 887—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 178497411HCID 178497411—
SolventWaterHCID 962—
ProductHCID 178524188HCID 178524188—

Reaction Conditions

Temperature50 °C

Reaction Steps

Aqueous 2 N sodium hydroxide solution (1.26 mL) was added to an MeOH (5 mL) solution of methyl 3-pyrrolidin-1-yl-5-(tetrazol-5-yl)benzoate (35.6 mg), and stirred at 50° C. for 2 hours and 30 minutes. With cooling with ice, 2 N hydrochloric acid (2.52 mL) and water were added to it, and the formed precipitate was taken out through filtration, washed with water and dried to obtain the title compound as a yellow powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08138197B2
Source datasetuspto-grants-2012_03
ORD IDord-ae5be70a46be4899abe8093537d39ee1
Source noteuspto-grants-2012_03