反应详情

In a 2.0-liter egg plant-type flask, a hydrochloric acid/methanol solution (500 mL) of 4-bromo-3,5-dihydroxybenzoic acid (50 g, 0.21 mol) was stirred with heating under reflux for 6 hours. Methanol was removed under reduced pressure to obtain a crude crystal. This was washed with hexane and chloroform to obtain the title compound as a colorless solid.

1. temperaturewith heating
2. temperatureunder reflux for 6 hours
3. customMethanol was removed under reduced pressure
4. customto obtain a crude crystal
5. washThis was washed with hexane and chloroform