反应详情

温度

50 °C

3,5-Diethoxy-4-(1-methyl-1H-pyrazol-4-yl)-benzoic acid methyl ester (895 mg) was dissolved in a mixed methanol/THF solution (16 mL, 5/3), aqueous 1 M NaOH solution (6 mL) was added to it, and stirred at 50° C. for 5 hours. The reaction liquid was cooled to room temperature, and aqueous 1 M HCl solution (6 mL) was added to it, and the solvent was evaporated away under reduced pressure. The resulting solid was taken out through filtration, washed with water and ether, and dried under reduced pressure to obtain the title compound as a pale yellow solid.

1. additionwas added to it
2. customThe reaction liquid
3. temperaturewas cooled to room temperature
4. customthe solvent was evaporated away under reduced pressure
5. filtrationThe resulting solid was taken out through filtration
6. washwashed with water and ether
7. customdried under reduced pressure