Hydrochloric Acid → HCID 57930907, compound

Participants

Reaction Steps

Methyl 3-ethoxy-5-methoxy-4-(1-methyl-1H-pyrazol-4-yl)benzoate (157 mg) was dissolved in a mixed solvent of methanol/THF (9 mL, 1/2), and aqueous 1 M NaOH solution (2.1 mL) was added to it and stirred at room temperature for 5 hours. Aqueous 1 M HCl solution (2.1 mL) was added to it, and the solvent was concentrated under reduced pressure. The obtained solid was removed through filtration, washed with water and ether, and dried under reduced pressure to obtain the title compound as a white solid.

Provenance & Evidence