HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 57930984, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | tert-Butyl 6-amino-4-oxo-3,4-dihydro-1'H-spiro[1-benzopyran-2,4'-piperidine]-1'-carboxylate | HCID 66524936 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 57930984 | HCID 57930984 | — |
Reaction Steps
Methyl chloridocarbonate was added to a solution of tert-butyl 6-amino-4-oxospiro[chroman-2,4′-piperidine]-1′-carboxylate in pyridine and stirred at room temperature for 6 hours. The solvent was removed under reduced pressure and the residue was purified by silicagel column chromatography (hexane/EtOAc) to obtain the intended compound as pale yellow foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138197B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-a132f8438ee3452e9ea1479697362e85 |
| Source note | uspto-grants-2012_03 |