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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1097005Generated: October 27, 2026

Hydrochloric Acid → HCID 178434226, compound

https://huagongshe.com/reaction/1097005

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1-(5-Bromo-3-methyl-1H-indazol-1-yl)ethan-1-oneHCID 59127382—
SolventMethanolHCID 887—
ProductHCID 178434226HCID 178434226—

Reaction Conditions

Temperature60 °C

Reaction Steps

1-Acetyl-5-bromo-3-methyl-1H-indazole (1.23 g) was added to the solution of hydrochloride in methanol (30 ml), and stirred for 30 min at 60° C. The mixture was concentrated under reduced pressure, and the residue was crystallized from mixed solvent of hexane and EtOAc to give the title compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08138197B2
Source datasetuspto-grants-2012_03
ORD IDord-2a8746bc7f0f4de9985697c071cabdf6
Source noteuspto-grants-2012_03