反应详情

温度

60 °C

1-Acetyl-5-bromo-3-methyl-1H-indazole (1.23 g) was added to the solution of hydrochloride in methanol (30 ml), and stirred for 30 min at 60° C. The mixture was concentrated under reduced pressure, and the residue was crystallized from mixed solvent of hexane and EtOAc to give the title compound as a yellow solid.

1. concentrationThe mixture was concentrated under reduced pressure
2. customthe residue was crystallized
3. additionfrom mixed solvent of hexane and EtOAc