2-Amino-2-methyl-1-propanol → HCID 11625425, compound

HRID 1097331Notes

Reaction equation

HRID 1097331 reaction equation
Cl[C:2]1[C:3]2[S:20][C:19]([NH2:21])=[N:18][C:4]=2[N:5]=[C:6]([S:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[C:11]=2[F:17])[N:7]=1.[NH2:22][C:23]([CH3:27])([CH3:26])[CH2:24][OH:25]>>[NH2:21][C:19]1[S:20][C:3]2[C:2]([NH:22][C:23]([CH3:27])([CH3:26])[CH2:24][OH:25])=[N:7][C:6]([S:8][CH2:9][C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[C:11]=3[F:17])=[N:5][C:4]=2[N:18]=1

Participants

3

Reactant 2

HCID 118072-Amino-2-methyl-1-propanolHCID 112216507-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine

Product 1

HCID 11625425HCID 11625425, compound

Procedure

Prepared by the method of example 2 step a), using the product of example 4, step b) and 2-amino-2-methylpropanol.

Workup

  1. customPrepared by the method of example 2 step a),

Sources & evidence

ORD record
ord-d4e940b7edb845578a6195a6bca4ee1b
Source dataset
uspto-grants-2012_03
Patent number
US08143261B2

Reaction notes

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