HCID 86657328, compound → HCID 12322860, compound

HRID 1097405Notes

Reaction equation

HRID 1097405 reaction equation
[CH:1]1[C:6]2[CH2:7][CH2:8][CH2:9][CH2:10][C:11](=[CH:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:5]=2[CH:4]=[CH:3][CH:2]=1>C(OCC)(=O)C.[Pd]>[CH:1]1[C:6]2[CH2:7][CH2:8][CH2:9][CH2:10][CH:11]([CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 1

HCID 86657328HCID 86657328, compound

Product 1

HCID 12322860HCID 12322860, compoundYield 99.3%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of ethyl (6,7,8,9-tetrahydro-5-benzocycloheptenylidene)acetate (0.550 g) in ethyl acetate (10 ml) was added with 10% palladium/carbon (0.055 g), and the mixture was stirred for 3 hours under a hydrogen flow. The reaction mixture was filtered through Celite, and then the solvent of the filtrate was concentrated under reduced pressure to obtain the title compound (0.551 g, yield: 99%).

Workup

  1. filtrationThe reaction mixture was filtered through Celite
  2. concentrationthe solvent of the filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-39043f1c2ba34e94bc103a80b7c87ffe
Source dataset
uspto-grants-2012_03
Patent number
US08143260B2

Reaction notes

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