反应详情

To a solution of 62 mg (0.252 mmol) 6-nitro-6-phenyl-octahydro-indolizine in 2.0 ml THF was added 150 ul Raney Nickel (50% in water). The mixture was stirred under a hydrogen atmosphere for 2 hours. The apparatus was purged with argon. The catalyst was filtered, washed with THF and the filtrate was concentrated in vacuo to provide 57 mg (y: 100%) of the title compound as a colorless oil. MS (m/e): 217.4 (M+H+).

1. customThe apparatus was purged with argon
2. filtrationThe catalyst was filtered
3. washwashed with THF
4. concentrationthe filtrate was concentrated in vacuo