Hydrochloric Acid → HCID 59395616, compound

Participants

Reaction Steps

A mixture of 2-(2-chloro-4-fluorophenyl)acetohydrazide (909 mg, 4.5 mmol) and DIPEA (0.817 ml, 4.7 mmol) in dry DCM (65 ml) was added over 20 min to 4-chlorobutyryl chloride (0.505 ml, 4.5 mmol) in dry DCM (5 ml). After 1.5 h, 2M HCl was added and the precipitated 4-chloro-N-[(2-chloro-4-fluorophenyl)acetyl]butanohydrazide was filtered off, washed with water and dried (1.24 g).

Provenance & Evidence