Hydrochloric Acid → HCID 24987660, compound

Participants

Reaction Steps

A solution of 0.25 g (0.45 mmol) (2-{6-chloro-3-[4-(2-oxo-2,3-dihydro-indol-1-yl)-piperidine-1-carbonyl]-indol-1-yl}-ethyl)-methyl-carbamic acid tert-butyl ester in 3.6 ml (4.5 mmol) of a 1.25 M solution of hydrochloric acid in methanol was stirred for 20 min. at 50° C. The reaction mixture was concentrated to dryness to give 0.21 g of the title compound as an off-white solid.

Provenance & Evidence