2-Amino-5-methylpyridine → HCID 57438623, compound

HRID 1098077Notes

Reaction equation

HRID 1098077 reaction equation
[C:1]([O:5]C)(=O)[CH2:2][OH:3].[NH2:7][C:8]1[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][N:9]=1>>[OH:3][CH2:2][C:1]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][N:9]=1)=[O:5]

Participants

3

Reactant 2

HCID 153482-Amino-5-methylpyridineHCID 66774Methyl Glycolate

Product 1

HCID 57438623HCID 57438623, compound

Procedure

The title compound was prepared in a manner similar to that described for Intermediate A3, starting from methyl glycolate and 2-amino-5-picoline, 1H NMR (300 MHz, CDCl3) δ 9.24 (br s, 1H), 8.19 (d, 1H), 8.07 (d, 1H), 7.57 (dd, 1H), 5.59 (br s, 1H), 4.26 (s, 2H), 2.31 (s, 3H).

Sources & evidence

ORD record
ord-6e052183311c46949f9767716ccbd8ba
Source dataset
uspto-grants-2012_03
Patent number
US08143263B2

Reaction notes

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