Methyl Glycolate → HCID 24284859, compound
Reaction equation
[C:1]([O:5]C)(=O)[CH2:2][OH:3].[NH2:7][C:8]1[S:9][CH:10]=[C:11]([CH3:13])[N:12]=1>>[OH:3][CH2:2][C:1]([NH:7][C:8]1[S:9][CH:10]=[C:11]([CH3:13])[N:12]=1)=[O:5]Participants
3
Procedure
The title compound was prepared in a manner similar to that described for Intermediate A3, starting from methyl glycolate and 2-amino-4-methylthiazole, 1H NMR (300 MHz, CDCl3) δ 10.11 (br s, 1H), 6.55 (s, 1H), 5.58 (br s, 1H), 4.36 (s, 2H), 2.34 (s, 3H).
Sources & evidence
- ORD record
- ord-2eae3e60c6374e15a48b5f905c7f0ad4
- Source dataset
- uspto-grants-2012_03
- Patent number
- US08143263B2
Reaction notes
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