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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1098086Generated: October 31, 2026

Diethyl Malonate → HCID 57438628, compound

https://huagongshe.com/reaction/1098086

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl MalonateHCID 7761—
Reactant2-Amino-5-methylpyridineHCID 15348—
Reactant2-Bromoethyl methyl etherHCID 80972—
ProductHCID 57438628HCID 57438628—

Reaction Steps

The title compound was prepared in a manner similar to that described for Intermediate A16 and Intermediate A2 (Step 2-Step 3) starting from diethyl malonate, 2-bromoethyl methyl ether and 2-amino-5-picoline, 1H NMR (300 MHz, CDCl3) δ 9.24 (br s, 1H), 8.14 (m, 2H), 7.52 (dd, 1H), 4.48 (br s, 1H), 4.39 (m, 1H), 3.69 (m, 2H), 3.39 (s, 3H), 2.25 (m, 4H), 2.09 (m, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143263B2
Source datasetuspto-grants-2012_03
ORD IDord-18942a8ddedb497aa11c1cd81af09eea
Source noteuspto-grants-2012_03