Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Azetidine | HCID 10422 | — |
| Reactant | Methyl (2S)-2-oxiranecarboxylate | HCID 10942355 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 66813606 | HCID 66813606 | 100% |
Reaction Steps
(S)-Methyl oxirane-2-carboxylate (1475 mg, 14.45 mmol) in acetonitrile (2 mL)was added to azetidine (825 mg, 14.45 mmol) in acetonitrile (8 mL). The reaction was heated to 100° C. for 60 minutes in the microwave reactor and cooled to room temperature. The mixture was evaporated to afford the crude product (2.3 g) which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08143263B2 |
|---|
| Source dataset | uspto-grants-2012_03 |
|---|
| ORD ID | ord-869f6e2f73bf4c8284c1f8ff9f542964 |
|---|
| Source note | uspto-grants-2012_03 |
|---|
