HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 3-methyl-1-(propan-2-yl)-1H-pyrazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 66728958 | HCID 66728958 | — |
| Product | 3-methyl-1-(propan-2-yl)-1H-pyrazole-4-carboxylic acid | HCID 14277911 | 79% |
Reaction Steps
In a procedure analogous to Example B6, ethyl 1-isopropyl-3-methyl-1H-pyrazole-4-carboxylate from Example B14 (91 mg, 0.464 mmol) and lithium hydroxide (78 mg, 1.855 mmol) were combined to afford 1-isopropyl-3-methyl-1H-pyrazole-4-carboxylic acid (62 mg, 79% yield). MS (ESI) m/z: 169.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143293B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-2a0533e944884df2a89b5bd36ced8ab3 |
| Source note | uspto-grants-2012_03 |