HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate → (S)-tert-butyl 3-oxo-4-phenylbutan-2-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate | HCID 11806530 | — |
| Reactant | HCID 178418336 | HCID 178418336 | — |
| Product | (S)-tert-butyl 3-oxo-4-phenylbutan-2-ylcarbamate | HCID 59634589 | — |
Reaction Steps
Prepared as described in Example 6 from (S)-tert-butyl 1-(methoxy(methyl)amino)-1-oxopropan-2-ylcarbamate (600 mg, 2.58 mmol) and benzylmagnesium chloride (2.0 M in THF, 3.87 mL, 7.75 mmol). Yield 653 mg (96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143290B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-bbfe277c401f4fe098a11a270f2bc182 |
| Source note | uspto-grants-2012_03 |